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Master's Dissertation
DOI
https://doi.org/10.11606/D.85.2021.tde-18112021-101714
Document
Author
Full name
Angélica Lins Linhares Peixoto Pinheiro
E-mail
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2021
Supervisor
Committee
Rostelato, Maria Elisa Chuery Martins (President)
Fernandes, Marco Antonio Rodrigues
Senna, André Machado de
Title in Portuguese
Perfil clínico e epidemiológico de mulheres com câncer de colo uterino no Norte do Estado do Tocantins durante o período de 2000 a 2015
Keywords in Portuguese
câncer
colo uterino
estudo epidemiológico
Abstract in Portuguese
O câncer (ca) de Colo de Útero é uma doença complexa, frequentemente relacionada à sua alta taxa de incidência, bem como sua letalidade em países não desenvolvidos como por exemplo o Brasil. Na Região Norte, este tumor se destaca, com índices alarmantes como por exemplo no Estado do Tocantins, em que as taxas se mostram bastante semelhantes aos índices observados na África Saariana. O presente estudo consiste em realizar um levantamento epidemiológico através da análise do perfil clínico de pacientes com Câncer de Colo de Útero no Norte do Tocantins atendidas no Hospital Regional de Araguaína (HRA) no período de 2000 a 2015. O objetivo do estudo consistiu em avaliar dados cadastrados pelo Sistema de Informação em Saúde do Registro Hospitalar de Câncer-SISRHC de 2664 mulheres. Foram incluídas pacientes entre os estadios 0 a IV. Foram analisadas 10 variáveis da Ficha de Registro de Tumor. O grau de completude dos dados escolhidos variou entre 67,5% e 100%. Foram analisadas as variáveis idade, raça, escolaridade, ocupação, estado conjugal, procedência, tipo histológico, histórico de tabaco e bebida alcoólica. O estadio predominante foi o IIIB. Os casos foram também subdivididos conforme o estadiamento em estadio precoce (0, I e II), e tardio (III e IV). Posteriormente foi realizada a associação entre as variáveis sociodemográficas com o estadiamento clínico precoce e tardio. Houve um aumento na porcentagem de casos de estadiamento tardio ao longo dos anos (p<0,001). Os fatores ocupação, raça, escolaridade e tabagismo foram bem definidos na incidência deste tumor, principalmente no caso de estadiamento tardio que foi predominante na amostra, trazendo uma grande preocupação já que diagnósticos realizados de forma tardia provocam muitos casos graves que por sua vez são responsáveis pelas formas mais agressivas desse tipo de câncer, levando consequentemente à alta taxa de mortalidade.
Title in English
Clinical and epidemiological profile of women with cervical câncer in the northern state of Tocantins during the period 2000 to 2015
Keywords in English
cancer
cervix
epidemiological study
Abstract in English
Cervical cancer (ca) is a complex disease, often related to its high incidence rate, as well as its lethality in undeveloped countries such as Brazil. In the North Region, this tumor stands out, with alarming rates, such as in the State of Tocantins, where rates are very similar to the rates observed in Saharan Africa. The present study consists of conducting an epidemiological survey through the analysis of the clinical profile of patients with Cervical Cancer in Northern Tocantins treated at the Hospital Regional de Araguaína (HRA) from 2000 to 2015. The objective of the study was to evaluate data registered by the Health Information System of the Hospital Cancer Registry - SISRHC of 2664 women. Patients between stages 0 to IV were included. 10 variables of the Tumor Registration Form were analyzed. The degree of completeness of the chosen data ranged between 67.5% and 100%. The variables age, race, education, occupation, marital status, origin, histological type, history of tobacco and alcoholic beverages were analyzed. The predominant stage was the IIIB. The cases were also subdivided according to the staging at an early stage (0, I and II), and a late stage (III and IV). Subsequently, an association was made between sociodemographic variables and early and late clinical staging. There was an increase in the percentage of cases of late staging over the years (p <0.001). The factors of occupation, race, education and smoking were well defined in the incidence of this tumor, especially in the case of late staging, which was predominant in the sample, causing great concern since diagnoses performed late cause many serious cases that, due to their instead they are responsible for the most aggressive forms of this type of cancer, consequently leading to a high mortality rate.
 
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Publishing Date
2021-11-29
 
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