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Master's Dissertation
DOI
10.11606/D.7.2014.tde-17042015-114518
Document
Author
Full name
Ana Paula da Conceição
E-mail
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2014
Supervisor
Committee
Cruz, Dina de Almeida Lopes Monteiro da (President)
Silva, Eneida Rejane Rabelo da
Silva, Rita de Cassia Gengo e
Title in Portuguese
Preditores da qualidade de vida relacionada à saúde de pacientes com insuficiência cardíaca
Keywords in Portuguese
Autocuidado
Cognição
Depressão
Enfermagem
Fadiga (Fisiologia)
Insuficiência cardíaca
Qualidade de Vida
Sono
Abstract in Portuguese
A insuficiência cardíaca (IC) é uma condição muito frequente, caracterizada por alta taxa de mortalidade e tem impacto negativo na qualidade de vida relacionada à saúde (QVRS). Este estudo teve como objetivo analisar fatores preditores da QVRS em pacientes com IC. Método: Estudo observacional, transversal, realizado com 409 pacientes com IC em tratamento ambulatorial. Variáveis sociodemográficas e clínicas, incluindo qualidade do sono (Pisttsburgh Sleep Quality Inventory), autocuidado (Self-Care of Heart Failure Index) e qualidade de vida relacionada à saúde (Minnesota Living With Heart Failure Questuionnaire) foram analisadas por meio de testes de associação e regressão logística binária múltipla. Resultados: Dos 409 pacientes avaliados: 224 (54,8%) eram do sexo masculino, tinham idade média de 57,9 anos (dp = 11,6), escolaridade média de 6,1 anos (dp = 4,1) e 60,2% tinham QVRS moderada/ruim. A QVRS moderada ou ruim foi associada a: ser do sexo feminino (p = 0,048), apresentar declínio cognitivo (p = 0,008), estar em classe funcional mais elevada (p < 0,001), ter sintomas depressivos (p < 0,001), ser mau dormidor (p < 0,001), ter fadiga e fadiga ocasionada pelo esforço (p < 0,001), ter dispneia (p < 0,001), noctúria (p < 0,001), fazer uso de 7 ou mais tipos de medicamentos (p < 0,001), tomar os medicamentos 9 vezes ou mais por dia (p < 0,002) e ter baixa atividade física habitual (p < 0,041). No modelo de análise múltipla, ser mau dormidor (OR = 2,5; p = 0,003), inadequada confiança no autocuidado (OR = 2,5; p = 0,009), estar na classe funcional mais elevada (OR = 3,7; p = 0,002), ter fadiga (OR = 3,3; p = 0,009) e fadiga ocasionada pelo esforço (OR = 8,7; p = < 0,001) e fazer uso de 7 ou mais tipos de medicamentos (OR = 3,2; p = 0,001) foram preditores independentes para a QVRS moderada ou ruim. Conclusões: A QVRS de pacientes com IC envolve fatores potencialmente modificáveis por intervenções não farmacológicas. Outros estudos de caráter longitudinal são necessários para confirmar a relevância desses fatores para a QVRS na insuficiência cardíaca.
Title in English
Predictors of health-related quality of life in patients with heart failure
Keywords in English
Cognition
Depression
Fatigue
Heart Failure
Nursing
Quality of Life
Self-care
Sleep
Abstract in English
Heart failure is a very common condition characterized by high mortality and has a negative impact on health-related quality of life (HRQOL). This study aimed to analyze potential predictors of HRQOL in patients with heart failure. Method: An observational, cross-sectional study conducted with 409 patients with HF in outpatient treatment. Sociodemographic and clinical variables, including sleep quality (Pisttsburgh Sleep Quality Inventory), self-care (Self-care of Heart Failure Index) and health-related quality of life (Minnesota Living With Heart Failure Questionnaire) were analyzed using tests of association and multiple binary logistic regression. Results: Out of 409 patients assessed, 224 (54.8%) were male, the mean age was 57.9 (SD 11.6) years, mean schooling was 6.1 (SD 4.1) years, and 60.2% had HRQOL moderate / poor. Moderate or poor HRQOL was associated with: female sex (p = 0.048), cognitive decline (p = 0.008), higher functional class (p <0.001), depressive symptoms (p <0.001), bad sleeper (p <0.001), fatigue and exertion fatigue (p <0.001), dyspnea (p <0.001), nocturia (p <0.001), making use of 7 or more kinds of drugs (p <0.001); having nine or more medications taken per day (p <0.002) and low habitual physical activity (p <0.041). In the multivariate analysis model, bad sleepers (OR = 2.5, p = 0.003), inadequate confidence in self-care (OR = 2.5, p = 0.009), higher functional class (OR = 3.7, p = 0.002), fatigue (OR = 3.3, p = 0.009), exertion fatigue (OR = 8.7, p = <0.001), use of seven or more kinds of drugs (OR = 3.2, p = 0.001) were independent predictors of moderate or poor HRQOL. Conclusions: HRQoL in heart failure patients with HF involves factors potentially modifiable by means of non-pharmacological interventions. Other studies of longitudinal design are needed to confirm the relevance of these factors to HRQOL in heart failure.
 
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Publishing Date
2015-07-14
 
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