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Doctoral Thesis
DOI
https://doi.org/10.11606/T.6.2004.tde-11012021-133708
Document
Author
Full name
Rubia Yuri Tomita
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2004
Supervisor
Committee
Beyruth, Zuleika (President)
Hirata, Rodobiko
Pereira, Denise Navas
Rocha, Aristides Almeida
Sáfadi, Regina Sawaia
Title in Portuguese
Toxicidade de mistura de agrotóxicos em ambiente aquático: reflexos na Saúde Pública da exposição simultânea aos herbicidas atrazina e diuron
Keywords in Portuguese
Atrazina
Daphnia similis
Diuron
Herbicida
Selenastrum capricornutum
Toxicidade de Mistura
Abstract in Portuguese
A avaliação da toxicidade de misturas de agrotóxicos é importante pois é cenário comum, principalmente no ambiente aquático, devido à utilização intensiva e simultânea dos compostos. Assim, foi desenvolvido estudo para comparar o efeito tóxico causado pelos herbicidas atrazina e diuron quando presentes individualmente e em mistura no ambiente aquático. Realizou-se teste de toxicidade aguda com alga Selenastrum capricornutum e com microcrustáceo Daphnia similis expondo-os à atrazina e diuron individualmente e à mistura dos dois compostos, utilizando os métodos da Associação Brasileira de Normas Técnicas, modificados. Após exposição individualizada aos compostos, o diuron (CE(1)50, 96h= 0,01 mg/L) mostrou-se 7 vezes mais tóxico para a alga do que a atrazina (CE(I)50, 96h= 0,07mglL). Para o microcrustáceo, diuron (CE(I)50, 48h= 1 ,49mg/L) foi cerca de 15 vezes mais tóxico do que atrazina (CE(I)50, 48h= 22,53mg/L). Nos ensaios onde os organismos estiveram expostos à mistura dos agrotóxicos, o efeito tóxico foi mais severo quando comparado às toxicidades individuais dos herbicidas estudados, para ambos os organismos. Dentre outros aspectos, concluiu-se que o diuron foi mais tóxico do que atrazina e que a toxicidade aguda dos compostos foi potencializada quando presentes simultaneamente, em mistura, para os organismos estudados, indicando que a toxicidade de misturas de agrotóxicos se constitui em área de pesquisa a ser explorada, inclusive porque não há consenso sobre como conduzir a avaliação de toxicidade de misturas.
Title in English
Toxicity of agrochemicals mixture in aquatic environment: reflection on public health due to simultaneous exposition to herbicides atrazine and diuron
Keywords in English
Atrazine
Daphnia similis
Diuron
Herbicide
Selenastrum capricornutum
Toxicity of Mixture
Abstract in English
The evaluation of toxicity of agrochemicals mixture is important because it is a commom scenery, specially in the aquatic environment, due to intensive and simultaneous use of compounds. Study has been developed to compare the toxic effect caused by herbicides atrazine and diuron when individually present or as mixture in aquatic environment. Acute toxicity test has been carried out with algae Selenastrum capricornutum and microcrustacean Daphnia similis exposed to atrazine and diuron individually or as mixture, using methods of "Associação Brasileira de Normas Técnicas" (ABNT), modified. After individual exposition to the compounds, diuron (96h, EC(I)50= 0,01 mg/L) showed to be 7 times more toxic to algae than atrazine (96h, EC(I)50= 0,07mg/L). To the microcrustacean, diuron (48h, EC(I)50= 1,49mg/L) showed to be 15 times more toxic than atrazine (48h, EC(I)50= 22,53mg/L). The assays where organisms had been exposed to the agrochemicals mixture, results showed that toxic effects were more severe, when compared to individual toxicities of the studied herbicides, for both organisms. Among other aspects, it was concluded that diuron was more toxic than atrazine to the organisms, and acute toxicity of the compounds were more potent when simultaneously present, as mixture, for the tested organisms, and it indicates a research field that must be explored, specially because there is no consensus related to the way for conducting the evaluation of mixtures toxicity.
 
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Publishing Date
2021-01-11
 
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