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Doctoral Thesis
DOI
10.11606/T.5.2006.tde-06022007-091127
Document
Author
Full name
Vivianne Higuchi Imagawa
E-mail
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2006
Supervisor
Committee
Posso, Irimar de Paula (President)
Kahhale, Soubhi
Matera, Julia Maria
Pimenta, Cibele Andrucioli de Mattos
Utiyama, Edivaldo Massazo
Title in Portuguese
Avaliação da eficácia analgésica de três doses diferentes da dipirona sódica em cadelas submetidas à ovariosalpingohisterectomia
Keywords in Portuguese
Analgesia
Cães
Dipirona
Dor
Pós-operatório
Abstract in Portuguese
O presente estudo, realizado de maneira prospectiva, comparativa, aleatória e duplamente cega, avaliou a eficácia analgésica da utilização de 15, 25 e 35 mg/kg de dipirona sódica para obtenção de analgesia no período pós-operatório de cadelas submetidas à ovariosalpingohisterectomia e comparadas ao placebo, por meio de parâmetros objetivos (FC, FR, presssão arterial, dosagem plasmática de epinefrina e norepinefrina e sérica de cortisol) e subjetivos (escalas de avaliação da dor). Com base nos resultados obtidos, pôde-se concluir que a dipirona sódica na dosagem de 15 mg/kg não mostrou diferença analgésica do placebo e as dosagens de 25 e 35 mg/kg são igualmente eficazes para obtenção de analgesia pós-operatória de boa qualidade.
Title in English
Evaluation of analgesic efficacy of dypirone by the comparison of three different doses in bitches submitted to ovariohysterectomy
Keywords in English
Analgesia
Dipyrone
Dogs
Pain
Postoperative pain
Abstract in English
This prospective, comparative, randomized and double-blinded study aimed to compare 15, 25 and 35mg/kg of dipyrone for analgesia during ovariohysterectomy post-operative period to placebo by using objective (HR, RR, BP, plasma catecholamines and serum cortisol) and subjective (pain scales) parameters. So, it could be concluded that 15 mg/kg of dipyrone didn`t show statistically significant difference from placebo and 25 and 35 mg/kg of dipyrone can offer equally good quality of post operative analgesia in bitches submitted to ovariohysterectomy.
 
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Publishing Date
2007-02-12
 
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