• JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
  • JoomlaWorks Simple Image Rotator
 
  Bookmark and Share
 
 
Doctoral Thesis
DOI
10.11606/T.5.2005.tde-27092005-130705
Document
Author
Full name
Jozélio Freire de Carvalho
E-mail
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2005
Supervisor
Committee
Bonfa, Eloisa Silva Dutra de Oliveira (President)
Costallat, Lilian Tereza Lavras
Laurindo, Ieda Maria Magalhães
Sato, Emilia Inoue
Silva, Clovis Artur Almeida da
Title in Portuguese
"Antilipoproteína lipase (LPL): um novo componente no complexo processo aterosclerótico do lúpus eritematoso sistêmico?"
Keywords in Portuguese
ARTERIOSCLEROSE/complicações
HIPERLIPIDEMIA/imunologia
INFLAMAÇÃO/etiologia
LIPASE LIPOPROTÉICA/imunologia
LÚPUS ERITEMATOSO SISTÊMICO/patologia
PROTEÍNA C-REATIVA/análise
Abstract in Portuguese
Dislipidemia é implicada no processo aterosclerótico do LES. A descrição de aLPL no LES associado a hipertrigliceridemia levou-nos a analisar esse anticorpo no contexto da inflamação envolvida na aterogênese. aLPL foi encontrado em 38% dos pacientes com LES com altos níveis de triglicérides. Correlação positiva significante foi observada entre aLPL e PCR, VHS, SLEDAI, anti-DNA, anti-cardiolipina e CH100 baixo. Análise de regressão múltipla confirmou a forte associação entre aLPL e PCR. Esses dados dão suporte à associação entre inflamação, resposta imune e dislipidemia, introduzindo o aLPL como um novo componente nos complexos eventos da aterogênese do LES
Title in English
Antilipoprotein lipase antibodies (aLPL): a new player in the complex atherosclerotic process in systemic lupus erythematosus?
Keywords in English
ARTERIOSCLEROSIS/complications
C-REACTIVE PROTEIN/analysis
HYPERLIPIDEMIA/immunology
INFLAMMATION/etiology
LIPOPROTEIN LIPASE/immunology
LUPUS ERYTHEMATOSUS SYSTEMIC/pathology
Abstract in English
Dyslipidemia is implicated in the atherosclerosis process of SLE. The description of aLPL in SLE associated with hypertrigliceridemia prompted us to analyze this antibody in the context of the inflammation involved in the atherogenesis. aLPL was found in 38 por cento of SLE patients with high levels of triglycerides. Significant positive correlation was observed between aLPL and CRP, ESR, SLEDAI, anti-DNA, anti-cardiolipin and low CH100. Multiple regression analysis confirmed the strong association between aLPL and CRP. These data support the link between inflammation, immune response and dyslipidemia, introducing anti-LPL as new player in the complex events of atherogenesis in SLE
 
WARNING - Viewing this document is conditioned on your acceptance of the following terms of use:
This document is only for private use for research and teaching activities. Reproduction for commercial use is forbidden. This rights cover the whole data about this document as well as its contents. Any uses or copies of this document in whole or in part must include the author's name.
Anexos.pdf (48.53 Kbytes)
Capaindice.pdf (17.81 Kbytes)
conclusoes.pdf (3.17 Kbytes)
discussao.pdf (11.07 Kbytes)
introducao.pdf (5.59 Kbytes)
Objetivos.pdf (2.54 Kbytes)
Pacientesemetodos.pdf (13.81 Kbytes)
Referencias.pdf (22.80 Kbytes)
Resultados.pdf (45.61 Kbytes)
Publishing Date
2005-10-05
 
WARNING: Learn what derived works are clicking here.
All rights of the thesis/dissertation are from the authors
Centro de Informática de São Carlos
Digital Library of Theses and Dissertations of USP. Copyright © 2001-2021. All rights reserved.