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Doctoral Thesis
DOI
10.11606/T.5.2004.tde-24102005-143648
Document
Author
Full name
Paulo de Tarso Jorge Medeiros
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2004
Supervisor
Committee
Martinelli Filho, Martino (President)
Dodinot, Bernard
Fernández, Edmundo Arteaga
Pimenta, João
Sarabanda, Alvaro Valentim Lima
Title in Portuguese
"Cardiomiopatia hipertrófica: importância dos eventos arrítmicos em pacientes com risco de morte súbita"
Keywords in Portuguese
ARRITMIA/complicações
DESFIBRILADORES IMPLANTÁVEIS
FATORES DE RISCO
MARCA-PASSO ARTIFICIAL
MIOCARDIOPATIA HIPERTRÓFICA/epidemiologia
MORTE SÚBITA CARDÍACA/prevenção & controle
SEGUIMENTOS
Abstract in Portuguese
Vinte e seis pacientes com cardiomiopatia hipertrófica e fatores de risco de morte súbita, foram submetidos a implante de cardioversor-desfibrilador implantável de dupla-câmara, com seguimento médio de 19 meses. Observou-se quatro choques em arritmias letais, 4 pacientes apresentaram TVNS e 5 taquiarritmias supraventriculares. Ocorreu um óbito.Conclusões: Observamos: TPSV em 19,2%; TVNS em 15,4% e TVS/FV em 15,4%. Nenhuma variável clínica ou demográfica, discriminou o comportamento clínico ou funcional pós-implante de CDI; a recorrência de síncope pós implante de CDI, não se associou à presença de eventos arrítmicos e a hipertrofia maior que 30 mm se associou à choque precoce do CDI (p=0,003).
Title in English
Hypertrophic cardiomyopathy: sudden cardiac death in high risk patients and the role of arrhythmias
Keywords in English
ARRYTHMIA/complications
CARDIOMYOPATHY HYPERTROPHIC/epidemiology
DEATH SUDDEN CARDIAC/prevention & control
DEFIBRILLATORS IMPLANTABLE
FOLLOW-UP STUDIES
PACEMAKER ARTIFICIAL
RISK FACTORS
Abstract in English
During 19 months of average follow-up period, we followed 26 patients with hypertrophic cardiomyopathy and high risk for sudden death, all treated by dual chamber implantable cardioverter-defibrillator. 4 patients had received appropriate ICD discharge, 4 patients with NSVT and 5 supraventricular arrhythmias. One death had occurred. Conclusions: we observed: supraventricular arrhythmias in 19,2%; NSVT in 15,4% and VT/VF in 15,4%. The clinical or demographic outcomes did not suggest any clinical or functional results after ICD implantation; syncope may occur after ICD implantation and no arrhythmias recordered by intracardiac electrograms and left-ventricular-wall thickness greater than 30 mm is associated with early ICD shocks (p=0,003).
 
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Publishing Date
2005-10-25
 
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