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Master's Dissertation
DOI
https://doi.org/10.11606/D.47.2020.tde-03082020-122150
Document
Author
Full name
Yanina Leon Uscapi
E-mail
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2020
Supervisor
Committee
Helene, André Frazão (President)
Mello, Claudia Berlim de
Pavão, Rodrigo
Title in Portuguese
Avaliação do aprendizado de sequências determinísticas e probabilísticas na doença de Parkinson
Keywords in Portuguese
Doença de Parkinson
Memória implícita
Sequências determinísticas
Sequências probabilísticas
Abstract in Portuguese
A perda progressiva de células dopaminérgicas nos gânglios da base é característica patológica da doença de Parkinson (DP), que resulta na disfunção de respostas automáticas motoras. O estudo se baseia no fato de que as disfunções motoras, de automaticidade e cognitivas compartilham a via córtico-estriatal, onde acontece esta perda dopaminérgica. Estudos dos componentes desta via detectaram ativação do estriato durante o aprendizado implícito. Por outro lado, estudos que mediram o tempo de reação em participantes com DP em diferentes tarefas revelaram correlações entre desempenho motor e aquisição implícita do conhecimento. O objetivo principal do presente trabalho é avaliar o aprendizado implícito de sequências probabilísticas na Doença de Parkinson
Title in English
Not informed by the author
Keywords in English
Deterministic sequences
Implicit knowledge acquisition
Parkinsons Disease
Probabilistic sequences
Abstract in English
The progressive loss of dopaminergic cells at the basal ganglia is a pathological aspect of Parkinsons Disease (PD) that results in the dysfunction of motor automatic responses. The present study is based on the fact that motor, automatic, and cognitive dysfunctions share the cortical striatum pathway, which suffers from dopaminergic loss. Past studies of this pathway components have shown the striatum activation during implicit learning. Although, studies that measured reaction time in individuals with PD at different tasks revealed correlations between motor performance and implicit knowledge acquisition. Our main goal is to evaluate the implicit learning of probabilistic sequences on Parkinsons Disease
 
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Publishing Date
2020-08-03
 
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