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Doctoral Thesis
DOI
Document
Author
Full name
Roberto Castro Júnior
E-mail
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2010
Supervisor
Committee
Moraes, José Carlos Teixeira de Barros (President)
Dib, Sérgio Atala
Gutierrez, Marco Antonio
Muhlen, Sérgio Santos
Pasqualucci, Silvia Helena Gelás Lage
Title in Portuguese
Glicosímetro de pulso
Keywords in Portuguese
Diagnóstico
Glicose (medição; instrumentos)
Abstract in Portuguese
Este trabalho descreve o desenvolvimento e a avaliação clínica de um instrumento para monitorização contínua e não-invasiva da concentração de glicose no sangue arterial adotando o mesmo método que a oximetria de pulso utiliza para determinação da saturação do sangue arterial. O sistema para medição de glicemia de pulso desenvolvido neste trabalho foi projetado a partir da utilização de um sensor óptico similar aos sensores de oximetria de pulso utilizando os comprimentos de onda de 805 e 1350 nm. Foi realizada uma avaliação clínica do instrumento com 20 voluntários masculinos e femininos entre 16 e 63 anos, de 48 a 112 kg e diferentes raças. Para estes voluntários, o instrumento apresentou uma exatidão (Arms) e desvio padrão (SDR) da ordem de 10 mg/dl, que podem ser considerados muito bons, quando comparado com monitores de glicemia do tipo ponta de dedo, que apresentam uma exatidão da leitura da ordem de 15 mg/dl para a faixa de medidas utilizada.
Title in English
Pulse glucometer.
Keywords in English
Diagnosis
Glucose (measurement; device)
Abstract in English
This paper describes the development and the clinical evaluation of a continuous non-invasive monitoring device for blood glucose concentration in arterial blood. The adopted method was the same one used in pulse oximetry for determining arterial blood saturation. The measurement system developed in this project to determine pulse blood glucose level was based on an optical sensor similar to the pulse oximetry sensors using wavelengths of 805 and 1350 nm. A clinical trial of the device was performed with 20 volunteers, both male and female, aged 16 to 63, weighting 48 to 112 kg and of different races. For this group of volunteers the device presented an accuracy (Arms) e standard deviation (SDR) in the magnitude of 10 mg/dl, considered very good when compared to blood glucose monitors of the fingertip type, which presents a reading accuracy in the magnitude of 15 mg/dl for the range of measurements employed.
 
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Publishing Date
2010-09-01
 
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