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Master's Dissertation
DOI
https://doi.org/10.11606/D.17.2021.tde-10052021-143844
Document
Author
Full name
Mirella Almeida de Oliveira
Institute/School/College
Knowledge Area
Date of Defense
Published
Ribeirão Preto, 2020
Supervisor
Committee
Paula, Jayter Silva de (President)
Schellini, Silvana Artioli
Vasconcellos, José Paulo Cabral de
Title in Portuguese
Análise de movimentos sacádicos durante tarefa de busca visual em pacientes com glaucoma primário de ângulo aberto
Keywords in Portuguese
Busca visual
Glaucoma
Movimento ocular
Perimetria visual
Visão periférica
Abstract in Portuguese
Introdução: O desempenho da busca visual (BV) está associado aos movimentos sacádicos (MS) e pode se relacionar com perdas na perimetria padrão automatizada (PPA), observadas em pacientes com glaucoma. Objetivo: Avaliar os MS em pacientes com perdas perimétricas em pacientes com glaucoma primário de ângulo aberto (GPAA). Casuística e Métodos: Treze participantes com boa acuidade visual (0,2 logMAR ou melhor) (7 GPAA e 6 controles) realizaram exame oftalmológico abrangente, incluindo a PPA (SITA-Fast 24-2) e uma tarefa de BV digital monocular exploratória, que quantifica o tempo para encontrar o número "4" em uma matriz aleatória de dígitos distribuídos na tela. Após ajustes de ângulo e distância, a tela foi espacialmente combinada com a PPA e dividida em cinco áreas para análise. Durante a tarefa, os MS foram registrados concomitantemente no mesmo olho com um rastreador ocular baseado em vídeo. Resultados: Pacientes com GPAA mostraram um número significativamente maior de MS/tela (média ± DP: 57,65 ± 31,86 vs. 38,94 ± 18,27, p=0,027) e tempo de BV (por tela: 49,72 ± 29,23 vs. 23,64 ± 5,45 segundos, p=0,035; e por alvo: 7,36 ± 4,09 vs. 3,58 ± 0,98 segundos, p=0,008) do que os controles. Embora a análise univariada tenha mostrado correlação significativa com MD (r= -0,40, p=0,02), apenas o tempo de BV/tela foi significativamente associado ao número de MS/tela no modelo de regressão multivariada (r=0,87, p<0,001). Não foi observada correlação significativa entre o número setorial de MS e a sensibilidade das cinco áreas da PPA. Conclusões: Pacientes com acuidade visual normal e perdas glaucomatosas localizadas na PPA apresentaram desempenho prejudicado de BV, demonstrando número aumentado de MS por tela, durante esta tarefa visual exploratória.
Title in English
Analysis of saccadic movements during visual search task in patients with primary open-angle glaucoma
Keywords in English
Eye movements
Glaucoma
Peripheral vision
Visual field
Visual search
Abstract in English
Introduction: Visual search (VS) performance is associated with saccades and may be correlated to peripheral visual field (VF) losses seen in glaucoma patients. Purpose: The aim of this stugy was to evaluate saccadic movements in patients with VF loss due to primary open-angle glaucoma (POAG). Casuistic and Methods: Thirteen participants with good visual acuity (0.2 logMAR or better) (7 POAG, and 6 Controls) yielded a comprehensive ophthalmological examination, including Humphrey VF tests (SITA-Fast 24-2), and performed a monocular, exploratory digital VS task, that quantifies the duration for finding the number "4" on a random array of digits distributed on the screen. After angle and distance adjustments, screen was spatially matched with VF, and divided in 5 areas for analysis. During the task, saccades were concomitantly recorded in the same eye with a video-based eye-tracker. Results: Patients with POAG showed a significantly higher number of saccades/screen (mean±SD: 57.65±31.86 vs. 38.94±18.27 saccades, p=0.027), and VS time (per screen: 49.72±29.23 vs. 23.64±5.45 seconds, p=0.035 and per stimulus: 7.36±4.09 vs. 3.58±0.98 seconds, p=0.008) than controls. Although univariate analysis showed a significant correlation with MD (r=-0.40, p=0.02), only the VS time/screen was significantly associated with the number of saccades/screen in the multivariate regression model (r=0.87, p<0.001). No significant correlation was observed between the sectorial number of saccades and the sensitivity of the five VF areas. Conclusions: Patients with normal visual acuity and localized glaucomatous VF losses showed impaired visual search performance, as well as an increased number of saccades per screen during this exploratory visual task.
 
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Publishing Date
2021-05-21
 
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