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Master's Dissertation
DOI
https://doi.org/10.11606/D.74.2013.tde-16092013-093144
Document
Author
Full name
Joao Francisco Lucon Junior
Institute/School/College
Knowledge Area
Date of Defense
Published
Pirassununga, 2013
Supervisor
Committee
Silva, Edson Roberto da (President)
Magalhães, Prislaine Pupolin
Martins, Ana Maria Centola Vidal
Title in Portuguese
Avaliação da atividade microbicida de extratos vegetais sobre Staphylococcus aureus isolados de mastite bovina
Keywords in Portuguese
Staphylococcus aureus
extratos vegetais
interação
mastite bovina
medicina popular
Abstract in Portuguese
A resistência bacteriana é responsável perante o fracasso no tratamento de infecções com agentes quimioterápicos. São necessárias novas alternativas para controlar estes micro-organismos. Entre essas alternativas estão plantas utilizadas tradicionalmente na medicina popular. O presente trabalho avaliou a eficiência dos extratos etanólicos e acetonicos de folhas de Cecropia pachystachya e Curatella americana com atividade antibacteriana in vitro em cepas de Staphylococcus aureus isolado de caso de mastite bovina. Os extratos de C. pachystachya e C. americana apresentam MIC de 2,5 mg.mL-1. O composto isolado de C. pachystachya denominado EEB2 apresentou actividade bactericida para uma concentração de 1,25 mg.mL-1. Estes resultados demonstram que os extratos de C. pachystachya e C. americana contém compostos anti-bacterianos.
Title in English
Evaluation of antibacterial activity of plant extracts on Staphylococcus aureus isolated from bovine mastitis
Keywords in English
Staphylococcus aureus
bovine mastitis
folk medicine
interaction
plant extracts
Abstract in English
Bacterial drug resistance is responsible for the failure of the treatment of infection using chemotherapeutic agents. Thus, new approaches are necessary for the control of these microorganisms. Included among these alternatives are several plants that are traditionally used in folk medicine. Therefore, the aim of this study was to evaluate the antibacterial activity of the ethanolic and acetone extracts of leaves of Cecropia pachystachya and Curatela americana in vitro against S. aureus bacteria isolates from cases of bovine mastitis. The extracts from C. pachystachya and Curatela americana had a MIC of 2.5 mg.mL-1. The compound isolated from C. pachystachya called EEB2 showed bactericidal activity at a concentration of 1.25 mg.mL-1. These results demonstrate that the extracts of C. pachystachya and C. americana contains antibacterial compounds.
 
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ME5114159COR.pdf (821.74 Kbytes)
Publishing Date
2013-09-16
 
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