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Master's Dissertation
DOI
https://doi.org/10.11606/D.55.2003.tde-22052003-203905
Document
Author
Full name
Cecilia Bollini Barboza Cid
E-mail
Institute/School/College
Knowledge Area
Date of Defense
Published
São Carlos, 2003
Supervisor
Committee
Oliveira, Aurelio Ribeiro Leite de (President)
Arenales, Marcos Nereu
Carvalho, Marcius Fabius Henriques de
Title in Portuguese
"Planejamento do tratamento por radioterapia através de métodos de pontos interiores"
Keywords in Portuguese
métodos de pontos interiores
programação linear
radioterapia
Abstract in Portuguese
O objetivo deste trabalho consiste no desenvolvimento, estudo e implementação de métodos de pontos interiores específicos para o problema de planejamento do tratamento de câncer por radioterapia. Este é um problema de grande porte que contém uma estrutura matricial particular. A exploração desta estrutura de forma eficiente obtém bom desempenho computacional, através da redução da dimensão dos sistemas lineares que devem ser resolvidos a cada iteração, agilizando a definição de um tratamento adequado, uma vez que tipicamente várias simulações são realizadas antes da definição de um plano definitivo. Resultados numéricos em Matlab ilustram a eficiência desta abordagem em problemas reais e mostram a superioridade do método preditor corretor em comparação ao método primal-dual.
Title in English
Specialized Interior Point Methods for Radiotherapy Treatment Design
Keywords in English
interior point methods
linear programming
radiotherapy
Abstract in English
In this work, a specialized interior point method is developed for planning cancer treatment by radiotherapy. This is a large-scale problem with a specific matrix structure. That structure is explored in an efficient way reducing the dimension of the linear system which must be solved at each iteration speeding up the treatment design since usually several versions must be solved to obtain a satisfactory plan. Moreover, the system obtained is sparse, symmetric and positive definite. Numerical results in Matlab illustrate the efficiency of this approach in real problems and show the superiority of the preditor-corrector method in comparison to the primal-dual method.
 
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Tese.pdf (289.93 Kbytes)
Publishing Date
2003-07-16
 
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