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Doctoral Thesis
DOI
https://doi.org/10.11606/T.5.2006.tde-14092006-120301
Document
Author
Full name
Cláudia Adriana Sant'Anna Ferreira
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2005
Supervisor
Committee
Cukier, Alberto (President)
Chiavegato, Luciana Dias
Jardim, José Roberto de Brito
Ribeiro, Marcos
Velloso, Marcelo
Title in Portuguese
"Efeito da oxigenoterapia e dos broncodilatadores no desempenho físico de pacientes com DPOC"
Keywords in Portuguese
Broncodilatadores
Dispnéia
Doença pulmonar obstrutiva crônica/terapia
Exercício
Oxigenoterapia
Abstract in Portuguese
Nosso objetivo foi avaliar o efeito do oxigênio (O2) e dos broncodilatadores (BD) sozinhos ou associados, no alívio da dispnéia e desempenho físico. Foram feitas inalação de 5 mg de salbutamol + 500 ug de brometo de ipratrópio seguidas de teste dos seis minutos com O2 ou ar comprimido em 28 pacientes com DPOC, dispnéia aos esforços e SaO2 menor que 89%. Resultados: a distância no teste de caminhada aumentou de 356 (128)m para 377(117)m após BD (p menor 0,05), para 406 (109)m após O2 (p=0,011 comparado com BD+ar e p=0,001 quando comparado com inalação placebo+ar). A dispnéia foi significantemente menor somente com a combinação do O2 com BD e o efeito do oxigênio na capacidade física foi potencializado pela administração prévia de BD
Title in English
The exercise of bronchodilatadors and oxygen alone and in combination on exercise performance in COPD
Keywords in English
Bronchodilator agents
Dyspnea
Exercise
Oxygen inhalation therapy
Pulmonary disease chronic obstructive/therapy
Abstract in English
Our objective was assess the effect of oxygen (O2) and bronchodilator (BD) on reduce exertional breathlessness and improve exercise tolerance in patients with COPD. Nebulization of 5 mg of salbutamol plus 500 ug ipratropium bromide followed by a six-minute walking test while breathing O2 were studient in 28 patients with severe COPD, breathless on exertion and with SaO2 menor que 89%. Results: The distance increased from 356 (128)m to 377 (117)m after the BD (p menor 0,05), to 406 (109)m after O2 (p 0,001 vs placebo/air). End-exercise dyspnoea only fell significantly when O2 and BD were combined and the effect of O2 on exercise preformance was improvement with therapies combined
 
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Publishing Date
2006-09-15
 
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