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Master's Dissertation
DOI
10.11606/D.5.2006.tde-03052006-133432
Document
Author
Full name
Celia Regina Furucho Yamamoto
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2006
Supervisor
Committee
Yasuda, Maria Aparecida Shikanai (President)
Abrahamsohn, Ises de Almeida
Carvalho, Silvino Alves de
Title in Portuguese
"Diagnóstico da doença de Chagas em bancos de sangue: linfoproliferação, detecção de anticorpos e estudo epidemiológico em indivíduos com provas sorológicas inconclusivas"
Keywords in Portuguese
Bancos de sangue/métodos
Doença de Chagas/diagnóstico
Doença de Chagas/epidemiologia
Elisa/métodos
Linfócitos
Testes sorológicos
Trypanosoma cruzi/imunologia
Western blotting
Abstract in Portuguese
O objetivo deste estudo foi avaliar a contribuição de linfoproliferação (1 parâmetro) em associação a provas sorológicas de alto desempenho (4 parâmetros), estudo epidemiológico (1) e parasitológico (1) em indivíduos com sorologia convencional inconclusiva para a doença de Chagas. Mostramos que o diagnóstico de doença de Chagas é provável quando 3 ou mais desses parâmetros são positivos em 7 (15/73). A combinação: TESA-blot e linfoproliferação positivos revelou-se útil diante de antecedentes epidemiológicos positivos
Title in English
Diagnostic of Chagas disease in blood banks: lymphoproliferation, antibodies detection and epidemiological data in individuals with inconclusive serology
Keywords in English
Blood banks/methods
Blotting Western
Chagas disease/diagnosis
Chagas disease/epidemiology
Enzyme-linked immunosorbent assay/methods
Lymphocytes
Serologic tests
Trypanosoma cruzi/immunology
Abstract in English
This study aims to evaluate the contribution of lymphoproliferation (1 parameter) in association with high performance serological tests (4), epidemiological data (1) and parasitological tests (1) for Chagas disease in patients with inconclusive conventional serological tests. We showed that this diagnosis is probable in individuals presenting > three positive of these 7 parameters (15 of 73 individuals). The combination of TESA-blot, lymphoproliferation was useful when epidemiological data were positive
 
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CeliaReginaFurucho.pdf (192.28 Kbytes)
Publishing Date
2006-05-15
 
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