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Doctoral Thesis
DOI
https://doi.org/10.11606/T.5.2007.tde-12022009-133543
Document
Author
Full name
Joaquim Adolfo de Freitas Silveira
E-mail
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2007
Supervisor
Committee
Margarido, Nelson Fontana (President)
Corsi, Paulo Roberto
Massarollo, Paulo Celso Bosco
Paula, Roberto Anania de
Tannuri, Uenis
Title in Portuguese
Avaliação da utilização de sistema de suspensão abdominal mecânica: estudo experimental em cães
Keywords in Portuguese
Cães
Fisiologia respiratória
Laparoscopia/métodos
Pneumoperitônio artificial
Processos hemodinâmicos
Abstract in Portuguese
Com o intuito de avaliar sistema de suspensão mecânica da parede abdominal, elaborou-se protocolo experimental, estudando-se trinta cães, distribuídos em três grupos experimentais de maneira aleatória: grupo pneumoperitônio com gás carbônico, grupo suspensão pela cavidade peritoneal e grupo suspensão abdominal (intraperitoneal) pela tela subcutânea, para documentar alterações metabólicas, hemodinâmicas e respiratórias em cada grupo, compará-las e verificar possíveis vantagens ou desvantagens dos métodos. Os animais foram monitorizados com eletrocardiograma, cateter de Swan-Ganz e pressão arterial invasiva, sendo colhidas amostras de sangue arterial e venoso misto nos momentos basal, 0, 15, 30, 60, 90, 120 minutos e 30 minutos após o término do procedimento, anotando-se para cada momento os parâmetros hemodinâmicos. Calculouse a média e o desvio padrão dos parâmetros, sendo os diferentes grupos comparados pelo teste de Kruskal-Wallis, e nos momentos em que se encontrou diferença estatística entre os três grupos, comparou-se os grupos dois a dois pelo teste de Mann-Whitney. Observou-se, no grupo pneumoperitônio em relação aos grupos suspensão, queda significativa do pH sangüíneo, elevação do bicarbonato, elevação da pressão venosa central e elevação da pressão parcial de gás carbônico, diferenças estas estatisticamente significativas, com p<0,05, não havendo diferenças estatísticas entre os grupos suspensão abdominal e subcutânea
Title in English
Evaluation of abdominal wall lifting system utilization: experimental study in dogs
Keywords in English
Dogs
Hemodynamics process
Laparoscopy/methods
Pneumoperitoneum artificial
Respiratory physiology
Abstract in English
With the purpose of evaluate abdominal wall lifting system, a experimental protocol was elaborated, and thirty dogs, distributed randomly in three experimental groups, pneumoperitoneum with carbon dioxide gas, abdominal (intraperitoneal) suspension and subcutaneous suspension, were studied to document metabolic, hemodynamic and respiratory alterations, compare then and verify if there are some advantage or disadvantage in each method. The animals were monitored with electrocardiogram, Swan-Ganz catheter and invasive arterial blood pressure, and samples of arterial and venous blood were collected at the moments basal, 0, 15, 30, 60, 90 and 120 minutes, and 30 minutes after the end of procedure, registering at each moment the hemodynamical parameters. The three groups were statically compared with Kruskal-Wallis test and, at the moments with statistical differences, the groups were compared two by two with Mann-Whitney test. At the group pneumoperitoneum was observed significant decrease of blood pH, raising of bicarbonate, central venous pressure, and partial carbon dioxide blood pressure in relation to suspension groups, and those differences were statistically significant with p<0.05, without significant differences between abdominal and subcutaneous suspension groups
 
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Joaquimfsilveira.pdf (2.38 Mbytes)
Publishing Date
2009-03-27
 
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