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Master's Dissertation
DOI
https://doi.org/10.11606/D.42.2008.tde-30052008-122009
Document
Author
Full name
Gisele Reisdoerfer
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2008
Supervisor
Committee
Chopard, Renato Paulo
Mitre, Anuar Ibrahim
Souza, Romeu Rodrigues de
Title in Portuguese
Efeitos do envelhecimento nos componentes fibroelásticos da junção vésico-uretral de ratos wistar.
Keywords in Portuguese
Elastina
Envelhecimento
Incontinência urinária
Morfometria
Ratos
Trato urinário
Abstract in Portuguese
Para avaliar as fibras elásticas na junção vésico-uretral de ratos, em diferentes faixas etárias, realizou-se estudos histológicos, microscopia elêtronica e histomorfometria. O estudo histológico do sistema de fibras elásticas mostrou a presença dos três tipos de fibras elásticas, em todas as faixas etárias, a microscopia eletrônica de transmissão, mostrou as diferenças ultra-estruturais entre as fibras elásticas. A avaliação histomerfométrica revelou diminuição na densidade linear das fibras elásticas e oxitalânicas e aumento na das elaunínicas. Na junção vésico-uretral de animais velhos, há uma queda nas propriedades de elasticidade, recuo elástico e ancoragem, que são compensadas pelas fibras elaunínicas. O processo de envelhecimento das fibras elásticas na junção vésico-uretral não contribui sozinha e diretamente no estado de incontinência urinária, mas compensa e dá suporte a muscular, devido ao aumento das fibras elaunínicas, o que torna o sistema elástico na junção vésico-uretral indiretamente responsável pela manutenção da continência urinária.
Title in English
Effects of the aging in fibroelastics components of junction vesico-urethral in rat wistar.
Keywords in English
Aging
Elastin
Morphometry
Rat
Urinary incontinence
Urinary tract
Abstract in English
To evaluate the elastic fibers in the junctio vesico-urethral of the rat, in different age groups, was accomplished studies histologics, electron microcopy and histomorphometrics. Study histologic showed the presence of the three types elastic fibers in all the studied age groups, electron microcopy showed the ultra-structural differences amoung elastic fibers. Histomorphometric studies revealed a decrease the linear density of the mature elastic fibers and oxytalans and an increase elaunin. In the junction vesico-urethral of the old animals there is a fall the properties elastic, elastic recoil and achorage, but they are compensated by elaunins. Processs aging of the elastic system in this place doesn?t contribute alone or directly in urinary incontinence, but it is indirectly responsible for the maintenance urinary continence.
 
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Publishing Date
2008-06-10
 
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