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Doctoral Thesis
DOI
https://doi.org/10.11606/T.10.2016.tde-08042015-115314
Document
Author
Full name
Enoch Brandão de Souza Meira Junior
E-mail
Institute/School/College
Knowledge Area
Date of Defense
Published
São Paulo, 2014
Supervisor
Committee
Nassar, Alessandra Figueiredo de Castro
Rizzo, Huber
Title in Portuguese
Estudo comparativo entre tratamentos para as endometrites dos graus II e III em bovinos
Keywords in Portuguese
Antibiótico
Bovinos
Endometrite
Histeroscopia
Tratamento
Abstract in Portuguese
As endometrites representam um entrave à produção de bovinos leiteiros, à medida que a enfermidade diminui a fertilidade dos rebanhos e causa muitos prejuízos ligados ao custo de tratamento e perda produtiva. Este trabalho avaliou a validade e a eficiência do tratamento com Cefapirina, Ceftiofur e Oxitetraciclina. Para isso 120 animais diagnosticados com endometrite graus II e III pela técnica de histeroscopia fluida foram divididos em 4 grupos de 30 animais, sendo grupo controle (não tratado), um grupo tratado com 500 mg i.u. de Cefapirina, um grupo tratado com 6,6 mg/Kg de Ceftiofur e um grupo recebeu uma infusão de 4g de Oxitetraciclina i.u.. Os animais foram avaliados 4 vezes ou até alcançarem a cura. Avaliou-se o escore de condição corporal, a involução uterina por meio da mensuração dos diâmetros de cérvix e cornos uterinos, a presença e a característica do conteúdo uterino, o padrão hemodinâmico do útero, a resposta de citologia endometrial e a saúde endometrial por meio da histeroscopia. Os animais tratados com Cefapirina e Ceftiofur apresentaram diminuição da proporção de polimorfonucleares nas células recuperadas para citologia endometrial (P = 0,028). Todos os tratamentos apresentaram taxas de cura superior a do grupo controle, os tratamentos apresentaram taxa de cura pelo menos 23% superior a do controle (P = 0,042), porém não houve diferença entre os grupos. Não houve diferença na velocidade de cura entre os tratamentos. Em conclusão o emprego de tratamentos para endometrite é uma conduta aconselhável. Todos os tratamentos testados neste estudo obtiveram eficiência semelhante
Title in English
Comparative study on treatments to bovine endometritis degrees II and III.
Keywords in English
Antibiotic
Bovines
Endometritis
Hysteroscopy
Treatment
Abstract in English
Endometritis is a great barrier to the dairy production, as it diminishes fertility and causes economical losses with treatment costs and lowering production. This work has evaluated the value and the efficacy of the use of Cephapirin, Ceftiofur, and Oxitetracyclin for endometritis treatment. 120 animals were diagnosed with grade II and III endometrites trough hyteroscopic examination, and were allocated in four groups of 30 animals, control group (no treatment), Cephapin, that received i.u. Infusion of 500 mg of Cephapirin, Ceftiofur, received s.c. 6.6 mg/kg of Ceftiofur, and Oxitetracyclin, that got treated with i.u. Infusion of 4g of Oxitetracyclin. The animals were evaluated for four times or until they reached cure. Body condition score, Uterine involution assessed by ultrasound measurement of cervix and uterine horns, presence and the characteristic of uterine content, uterine hemodynamic patterns, cytology response, and uterine health response to treatment assessed by hysteroscopy were evaluated at each examination. Cows treated with Cephapirin and Ceftiofur presented a drop on the proportion of PMN retrieved at endometrial cytology examination (P = 0,028). All the treatments presented a bigger rate of cure than control group, at least 23% higher (P = 0,042); however, there was no difference among treatments. There was no difference on cure time among treatments. In conclusion, treating endometritis is an advisable conduct. All the treatments tested in this trial were equally efficient
 
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Publishing Date
2016-10-07
 
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